Special feature of 1905 film network In an office building in Dongcheng District, Jan Heinze, executive producer of PIXOMONDO, opened his eyes wide in front of the camera: "China is an exciting market. We have only been here for five years and have witnessed its tremendous changes, which are unbelievable. "

Just last week, Jiang Wen’s highly anticipated new work "One Step Away" was officially released. After a series of twists and turns, such as censorship, dubbing, and the cancellation of the premiere, One Step Away confidently entered the cinema and left the heated discussion to the fans. As of December 23rd, the cumulative box office of One Step Away has reached 380 million yuan. The magnificent colors and dreamy style of the film must still stay in your mind, and it is the German "Oscar-level" special effects company PIXOMONDO that helped Jiang Wen create this "magic realism" masterpiece. Recently, 1905 Film Network visited PIXOMONDO Beijing Branch exclusively to reveal the special effects industry hidden behind the film.

"Boutique-style" operation: resource sharing for 8 branches in the global market.

Maybe you haven’t heard of PIXOMONDO at all, but its works can list a must-see list for fans: Hugo, iron man 2, The Hunger Games, Snow White and the Hunter, Fast and Furious 5, Farewell Atlantis, Star Trek: Dark Boundless … … PIXOMONDO won the Best Visual Effects Award (Hugo) at the 84th Academy Awards in 2012 and the Best Special Effects Award (Game of Thrones) at the 63rd Emmy Awards. How did this mysterious behind-the-scenes team work, and how did they get together with director Jiang Wen?

Ten years ago, many films had almost no special effects, but now it is different. Even a small-budget love movie will have several special effects shots. "If you look at last year’s box office data, you will find that the top ten are special effects blockbusters. For filmmakers, special effects are tools that can shoot things that are impossible in reality, help explain the stories in movies, and create a whole new world. " Jan believes that special effects can actually be divided into two categories. Due to technical reasons, some special effects are easily visible to the audience, while others are more reflected in the imagination, which helps to increase the richness of the story.

Christoph Zollinger (hereinafter referred to as Chris), the visual effects producer of One Step Away, added: "Special effects make the visual elements and story statements of a movie more complete. For sci-fi films, which are particularly dazzling, artistic drive and technical means are indispensable. Fortunately, now is the digital age, and we can easily make many pictures that we can’t shoot in reality. Special effects producers are also storytellers and filmmakers to explore and realize those unknown things. "

Pixomondo was founded in Germany in 2001, with 8 studios in the United States, Canada, Germany and China. Unlike those big companies with 500 or 600 employees, PIXOMONDO’s eight studios are not large in scale, and the most special thing is that they have a clear division of labor and cooperation with each other. "We are more like a boutique. We focus on a variety of markets around the world, and Hollywood is just one of them. " Jan shrugged his shoulders, as if he was helpless about people’s prejudice against special effects. Every studio in PIXOMONDO will share talents, resources, film projects and so on, and sometimes eight studios will start work at the same time for a film. "We started five when we were doing One Step away."

To do special effects, you should also be able to "tell stories": "One step away" takes a year and a half to set the picture style.

It is said that Jiang Wencai found PIXOMONDO on the recommendation of martin scorsese. Perhaps it is the dazzling colors of European movies in Hugo that attracted him, or the same retro storyline is more likely to resonate. PIXOMONDO visual artists began to get involved in the film project one and a half years before the filming of One Step Away. Chris stressed: "Compared with previous film projects, this one is very different. PIXOMONDO Beijing Studio played a leading role for the first time. "

In people’s impression, special effects seem to be just a processing link on the film production line, such as ornaments on the Christmas tree, which are responsible for creating a glamorous appearance. Jan corrected in the interview: "Nowadays, special effects companies will not define themselves by what kind of technological means. Post-production is just a means. We should think about how to combine technology with storytelling and become a director or screenwriter ourselves." Hundreds of people participated in the production of One Step Away, and PIXOMONDO was involved in the pre-planning from the beginning to help determine the overall visual style of the film.

This article comes from WeChat WeChat official account:　8-word intersection (id: crosseight), Author: Han Sai, original title: "Participate in the African version of" Win in China ",what did Ma Yun say? 》, the title map comes from: vision china

On November 16, 2019, local time, a TV studio in Accra, the capital of Ghana, an African country.

On the stage stood ten young people, men and women, black and white. Ten smiling and confident faces looked at the camera under the stage.

On the big screen behind them, a row of English is displayed:

Africa’s Business Heroes(African business hero)

Under the stage, four judges, three men and one woman, sat in danger.

Two Africans, respectively, are Zimbabwe’s telecom tycoon Straf Mahiywa.(Strive Masiyiwa)And Ibkun Awosika, a Nigerian female banker.(Ibukun Awosika).

Outstanding African entrepreneurs in these years.

The other two Asian faces are Cai Chongxin, executive vice chairman of Alibaba’s board of directors, and the one who just stepped down as chairman of Alibaba’s board of directors not long ago:

Ma yun

Ten young people are carefully selected from more than 10,000 entrepreneurs in more than 50 countries in Africa.

They need to tell their dreams in front of the camera, introduce their projects, and accept comments from four judges to compete for a total of $1 million in venture capital.

Ten years ago, a similar program in China was all the rage. It was called Win in China.

Ma Yun is also a judge.

01

The first one is a girl from Rwanda, Kevin Kejirimpudu.（Kevine Kagirimpundu）.

Her entrepreneurial project is to make a pair of shoes worn by Rwandans.

The reason that prompted her to start this career was that walking in the streets of Rwanda, she often saw various shoe repair shops, but a large number of people were barefoot.

The reason behind this is that Rwanda’s light industry is very backward, and its shoes and socks are basically imported. Local shoe repairers can only repair shoes, and no one can make shoes.

After a long time, many local people go barefoot all the year round.

Discovering this market, she decided to teach herself and do it herself.

The first step is to search in Google:

How to make a pair of shoes?

According to the steps provided on the internet, Kevin began to practice his hands by using the existing materials at hand-discarded tires that can be seen everywhere on the streets of Rwanda. How to cut the sole, how to polish the leather, how to stick, and how to sew. ……

After several months of trying and consulting the shoe repairer repeatedly, she finally made the first pair of shoes and founded her own footwear brand, employing 70% female employees.

The raw materials she uses basically come from waste tires. This is also a practice of environmental protection.

Are you wearing shoes made by yourself now? Judge Straff asked suddenly.

Kevin standing on the stage directly took off his shoes and sent them to him barefoot.

Sure! You see, there is my company’s LOGO…… in it … I’m so embarrassed!

The audience burst into laughter, and Ma Yun sitting next to him also laughed.

This is far from his first contact with Africa and the young people here.

Two years ago, in 2017, Ma Yun gave a speech to thousands of young people in the university auditorium in Nairobi, Kenya.

In particular, he highlighted his failure to take the college entrance examination three times when he was young, and his failure to apply for a job 30 times to encourage young people to stick to their dreams.

In the cheers of the young people in the audience, Ma Yun said on the spot:

From now on, I will come to Africa every year and visit three African countries. I hope I can visit all 54 African countries in the next 10 to 15 years.

02

Vaccine promotion, agricultural technology, palm oil … One contestant after another came on stage to tell their dreams.

Their dreams are often linked to the suffering of the African continent.

In 1994, the biggest news that shocked the world came from Africa.

This year, a humanitarian disaster broke out in Rwanda, which is destined to be written into human history.

A few years ago, a civil war broke out between Hutu and Tutsi, two major ethnic groups in China, which killed more than 1 million people in just three months and wiped out one seventh of the country’s total population. Many Chinese have seen the film Hotel Rwanda.

Rwandan girl Kristel Quezela（Christelle Kwizera）I was born in this year. Fortunately, her home was far from the front line of the conflict and was not affected.

But for Rwandans, the massacre is only part of the disaster. Even if you get away with it, you need to face many challenges and death traps in your life.

The biggest threat comes from the water that everyone can’t live without every day.

In sub-Saharan African countries, almost all of them face the problem of water shortage because of drought. In fact, except for a few areas, most countries have rivers flowing through them, and water shortage is not serious.

What is really lacking is a safe water source that can be used.

In Africa, many deadly diseases, cholera, dysentery, typhoid fever or polio viruses are hidden in surface water, and a large number of people get sick and die after drinking unclean surface water every year.

Many years after the massacre, people in Rwanda are still dying all the time-just because of water.

Quezela’s childhood was full of experiences of fetching water again and again.

As long as she can remember, she and her mother walked to a water point more than ten miles away every day, carrying nearly 20 kilograms, ranging from five or six hours to more than ten hours.

It can be said that most of the labor force in the whole family only do one thing when they are alive: fetch water.

In Rwanda, only a few big cities have a tap water network, which can provide safe groundwater. The annual use price is about 500 dollars, which is about a quarter of the income of an ordinary person.

During her college years, Quezela studied mechanical engineering. After graduation, she founded Rwanda Water Resources Company.

Since 2014, Rwanda Water Resources Company has drilled wells and installed pipelines in more than 90 residential areas all over the country, and built hundreds of tap water networks.

Their price is one-third to one-fifth of the government water supply network.

Ma Yun comments:

Your biggest competitor should be the Rwandan government, because they have been actively promoting water supply construction in recent years.

Only if you are faster than them, provide better services and make your competitors worry about you, can your company continue to survive and grow in the future.

In March this year, after visiting Africa, Ma Yun established the Ma Yun African Youth Entrepreneurship Fund with a total amount of 10 million US dollars.

This fund will spend 1 million yuan each year to support entrepreneurs in the next ten years.

The "African Business Heroes" to be broadcast on major TV stations is the first.

03

In 2009, Temi Jiwatobson, a Nigerian girl studying in the United States.（Temie Giwa-Tubosun）I signed up for an internship program and returned to Nigeria to participate in medical volunteer activities.

In her hometown, Tammy witnessed a scene that she will never forget in her life. A pregnant woman suffered from dystocia that lasted for three days.

Although the doctors and nurses tried their best to rescue them, they failed to recover them. The mother eventually bled heavily, resulting in the death of the baby.

To save the baby’s life, only an ordinary caesarean section is needed, or timely and sufficient blood supply is needed.

It looks like a common condition, but it is almost impossible in Nigeria.

Nigeria is the largest oil producer in Africa, selling oil to Britain, the United States, China and Japan. However, in the World Health Organization’s ranking of public health conditions, it ranks 187th in the world, ranking fourth from the bottom.

In Nigeria, local couples have an average of 5-8 children, with 814 deaths per 100,000 births. The main cause of death is postpartum hemorrhage.

Five years later, Tammy had her own family, was pregnant with a son, and also suffered from dystocia and bleeding during childbirth.

After a day’s struggle with fate, she has no strength, thinking about whether the fate of that pregnant woman will repeat itself on herself.

Fortunately, she has returned to America. The doctor gave her a blood transfusion easily and performed a caesarean section, saving the lives of mother and son.

After that, Temi, who returned to Nigeria, found:

This country is not short of blood, but information.

Because the information is not interoperable, some hospitals or blood stations store blood that has expired and thrown away, and some places have no blood available. The core issues are information and logistics.

In 2015, she founded a "life bank" based on this idea.（Lifebank）To build the largest virtual blood bank in Nigeria.

On the platform of Life Bank, the real-time reserve information of 60 large hospitals and blood banks in China is collected. Hospitals and patients can timely inquire about the nearest blood bank, the reserves of blood of different blood types and blood products, and make reservations at the first time.

Life bank, which provides information and blood distribution services, charges a service fee ranging from 10 to 50 dollars each time.

At first, motorcycles that can walk freely in the streets and lanes and speedboats that cross urban rivers were used to transport blood, and then drones were used.

Since its establishment four years ago, Life Bank has saved the lives of 5,300 Nigerians with its 7×24-hour service.

Temi said that her dream is not only the $20 million blood supply market in Africa, but also the $30 billion African medical market. In addition to transporting blood, Life Bank can also try to transport oxygen, medical equipment, vaccines and other medical supplies urgently needed in Africa.

Ibkun, a female banker familiar with Nigeria’s predicament, spoke highly of this project:

You can’t expand too fast. The market in Nigeria is huge, and your products are related to people’s lives. This sensitivity is bound to require you to be cautious in your business.

Ma spoke, serious, dry goods:

First, global vision, local success. Blood supply is enough, don’t think about anything else.

Second, it’s useless to take away ppt and show the future figures. It doesn’t matter how big the market is. Most entrepreneurs say how big the market is. The market has 10 thousand yuan, but you only earn five yuan. What’s the use?

I don’t like ppt. Your expected data in the future is very vague. Only the specific figures at present can reflect your achievements.

This is not the first time Ma Yun talked about blood in Africa.

He said something like this:

Africa needs hematopoiesis, not blood transfusion. Countries that give more money and children who give more money can’t make a difference.

What we have to do in the end is to support young people in Africa and make them change.

I hope that in the next 20 years, Africa will have at least 100 Alibaba and 1,000 Ma Yun.

During Ma Yun’s trip to Africa, an official of China’s local embassy also used a similar metaphor in his speech:

What about Africa? Ma Yun brought the answer.

One is environmental protection, and the other is the activities of Ma Yun Africa Venture Fund, which stimulates Africa’s endogenous motivation and cultivates local entrepreneurs.

Money can only be given for blood transfusion, and now it is for Africa to make its own blood.

04

Coming to this final, there are also African entrepreneurial projects created by copying the China model.

Walid Rahman, a young man from Cairo, Egypt, told a beautiful story. His project is to make an African version of Hungry.

According to him, in Egypt, more than 35% of the population and nearly 19 million Egyptians are obese. Among them, 3.6 million children are seriously overweight, but another 900,000 children suffer from anemia.

Therefore, his goal is to provide Egyptians with cheap and nutritious food and stay away from junk food.

In 2015, his online ordering platform "Mom" was launched in Cairo, employing all kinds of housewives and using the family kitchen to make food.

Users only need to pay a monthly membership fee of $9 to become members and enjoy free delivery service.

However, the reality is very skinny. In four years, Walid only attracted 7,000 users to register, and the number of orders per year was about 40,000.

Before the total population of 22.8 million in Cairo, this figure seemed to have little influence.

In contrast, China’s Hungry occupied Shanghai Jiaotong University with more than 20,000 people in the first year, and covered all of Shanghai in the second year, with more than 10,000 cooperative restaurants.

For this project that talks too much about ideas, judge Straff gave severe criticism:

I thought your scale was not good at first, but now I find there is something wrong with your figures.

When you introduce your project, you always emphasize nutrition, but it is often children who need to consider nutrition, and adults don’t have time to take care of so many nutrition problems.

You only cook so-called nutritious meals. How competitive can you be in front of Uber Eat (a takeaway service launched by Uber)?

For this project, Ma Yun pointed to the crux of the problem:

It is not a good idea to start a business, which is packaged with too many ideas and stories and lacks a business model.

Make the enterprise bigger first, and then talk about nutrition.

What an entrepreneur should do is to try to make things simple and not to put lipstick on monkeys.

The last project on stage has two CEOs. One speaks on the stage and the other sits under the stage.

Of the two people, one is good at operation and the other is good at financing strategy, so their work is generally mixed up, and whoever does it will do it. Their employees also report to both sides respectively.

A judge asked him why he didn’t come to the stage, and the CEO who came to the stage replied: His eloquence is not good, so I will speak out.

Ma Yun comments:

I had 18 founders and 20-30 businesses. It is impossible to have 20-30 CEOs. Why are there two CEOs? Four CTOs can do it, but two CEOs can’t.

A person has only one heart, so he can’t report his nose to his brain and his eyes to his heart.

Full house laughing and clapping.

After deliberation, four judges named the top three "African business heroes", and Temi, the founder of Life Bank, won the championship.

She will receive a prize of $250,000. Others share the remaining 750,000 in different amounts.

05

This time I went to Africa, Ma Yun was very busy.

In addition to participating in the "African Business Heroes", he also awarded prizes to the rangers who protected nature and animals, and visited many countries, running up to three times a day.

In every country, he was warmly received by the head of state of that country and was asked a question at the same time:

How can Africa learn from China better?

Ma Yun said to the young African people at the scene:

Seeing you is like seeing myself 20 years ago.

I tried to go to Silicon Valley for financing, and I hit a wall again and again. Because no one believes that the Internet in China will develop, and no one believes in China, because we have no credit cards and no logistics.

But because of this, there are opportunities for us entrepreneurs.

If China has everything, what else do we need?

In the past two months, Ma Yun has not been idle, even busier than before.

His schedule is full of public welfare, education, environmental protection, encouraging entrepreneurship and cultivating female leadership …

Africa is also a very important part of it.

He said:

People often ask me why China’s institutions want to protect African animals, and I want to say, why not China?

China and Africa, we live on the same earth, and we only have this earth. If the earth is sick, no one will be healthy.

Africa is a land of hope. Seeing African entrepreneurs, I feel like I saw myself 20 years ago.

This article comes from WeChat WeChat official account:　8-word intersection (id: crosseight), author: Hansel

　　Xinhua News Agency, Washington, June 13 th, financial observation: Trade policy is "fiercer than tiger" and American enterprises are miserable and embarrassed

　　Xinhua News Agency reporter Xu Yuan

　　The destructive trade policy of the American government is becoming the biggest threat to the development of American enterprises. In recent days, from enterprises to trade associations, from large companies to small and medium-sized enterprises, business people have criticized the US government’s protectionist measures.

　　On behalf of 661 American enterprises and trade associations, the American lobbying organization "Tariffs Hurt the Hinterland of the United States" sent a letter to US President Trump on 13th, urging the US government not to impose tariffs on goods imported from China, and to return to the negotiating table to reach a solution with China.

　　The open letter warns that American enterprises and trade associations are worried about the situation of tariff escalation. The increase in tariffs and the uncertainty surrounding Sino-US trade negotiations have caused market turmoil and posed a threat to the US economy.

　　According to the survey released by the Business Roundtable composed of executives of large American enterprises on the 12th, the "Economic Outlook Index" fell by 5.7 points to 89.5 points in the second quarter. This index reflects the sales expectations, capital expenditures and recruitment plans of American business executives for the next six months, and shows that American business circles are increasingly uneasy about the direction of US trade policy.

　　"(The US government’s trade policy) is increasing the risk of bad economic results," said Jamie Dimon, CEO of JPMorgan Chase and chairman of the Business Roundtable at the press conference that day. "The uncertainty of trade policy, the weak global economic growth and the inaction of the US government on other urgent public policy issues are worrying."

　　Tom Linebarger, chairman and CEO of Cummins, an American engine manufacturer, said that "trade (policy) is the most terrible threat to enterprise growth". He said that imposing tariffs on China’s goods exported to the United States would increase consumers’ costs and reduce the competitiveness of American enterprises.

　　American financial data software company predicts that due to the uncertain tariff policy and global economic prospects, for those multinational companies whose sales are more than half from outside the United States, their profits in the second quarter may drop by 9.3%. The company expects that Apple’s profit may drop by 14.6% in the second quarter, and Boeing’s profit may drop by as much as 43.7%.

　　The U.S. government previously announced that the tariff rate on the $200 billion list goods imported from China will be increased from 10% to 25% from May 10, 2019. The U.S. government also threatened to impose a 25% tariff on the remaining about $300 billion of goods exported from China to the United States, involving many end consumer goods.

　　Lorraine Hutchinson, an analyst at Bank of America Merrill Lynch, predicts that tariff escalation will lead to growth risks for American retail enterprises such as clothing. According to the semi-annual survey recently released by institute for supply management, about 59% of American enterprises indicated that increasing tariffs would lead to higher product prices. Wal-Mart, an American retail giant, also said that tariffs will force it to raise the retail price of goods.

　　Tariffs not only hit large enterprises, but also make life more difficult for small enterprises. USA Today reported a few days ago that the negative impact of tariffs has exhausted the energy of many small American enterprises because their cost digestion ability is worse than that of large enterprises. Adjusting the supply chain will cost hundreds of thousands or even millions of dollars, which is unbearable for many small enterprises.

　　In September 2013, the Shanghai Pilot Free Trade Zone was formally established and set sail. In September 2023, the construction of China’s Pilot Free Trade Zone ushered in its 10th anniversary. Starting from Shanghai’s 28.78 square kilometers, it has been continuously expanded to about 38,000 square kilometers. In the past ten years, after six expansions, there have been 21 free trade zones and Hainan Free Trade Ports across the country, forming an innovative pattern of reform and opening up covering the east, west, north and south, and coordinating the coastal, inland and border areas, which has effectively explored and accumulated valuable experience for comprehensively deepening reform and opening up.

　　Ten years of hard work has yielded fruitful results, and it has accumulated a lot of brilliance. In the past ten years, the Pilot Free Trade Zone has launched a large number of basic and pioneering reform and opening-up measures in line with international common rules, formed many landmark and leading institutional innovations, cultivated a number of internationally competitive industrial clusters, stood at the forefront of China’s high-level opening-up, actively served major regional strategies, coordinated regional development strategies and jointly built the "Belt and Road", and achieved remarkable results.

　　In the past ten years, a total of 302 institutional innovations have gone from the China Pilot Free Trade Zone to the whole country, and more than 2,800 have been promoted and copied by various provinces, autonomous regions and municipalities, giving full play to the demonstration, leading and driving role of the Pilot Free Trade Zone, forming a good situation of sharing reform dividends and opening up the fruits to all. In 2022, the actual use of foreign capital in 21 pilot free trade zones was 222.52 billion yuan, accounting for 18.1% of the country. Among them, the actual use of foreign capital in high-tech industries was 86.34 billion yuan, a year-on-year increase of 53.2%. The total import and export volume of 21 pilot free trade zones reached 7.5 trillion yuan, up 14.5% year-on-year, accounting for 17.8% of the country; In the first half of this year, 21 pilot free trade zones accounted for 18.4% of the country’s foreign investment with a land area of less than four thousandths, and the actually used foreign capital reached 129.66 billion yuan, an increase of 8.2% year-on-year.

　　Since its establishment, China Pilot Free Trade Zone has been guided by high-level opening, and has made great efforts to explore an institutional system linked with international economic and trade rules. It has also made important breakthroughs in trade, investment, finance, and transformation of government functions, including taking the lead in implementing the national treatment plus negative list management model before foreign investment access, taking the lead in establishing a trade facilitation model centered on the "single window" of international trade, taking the lead in promoting the comprehensive opening of the service industry represented by the negative list management model of cross-border service trade, and taking the lead in implementing the "license separation". … In the past ten years, a number of firsts have been practiced and explored in the Pilot Free Trade Zone and copied to the whole country, creating a vivid model of China’s opening up and development, becoming the "vanguard" leading the country’s deepening reform in the new era, injecting stabilizers and providing new impetus for China’s economic stability and prosperity.

　　Bold trials, bold ventures and independent reforms, the fruitful results achieved in the Pilot Free Trade Zone in the past ten years come from innovation and opening up. Through a series of pioneering practices, the Pilot Free Trade Zone has continuously promoted the liberalization and facilitation of trade and investment and continued to lead the opening up. Since 2013, the negative list of foreign investment access in the Pilot Free Trade Zone has been reduced seven times, from 190 to 27 today, realizing the clearing of manufacturing items and the continuous expansion of service industry opening. Hainan Free Trade Port launched the first negative list of cross-border service trade, which realized the fundamental change of service trade management mode.

　　In addition, 21 pilot free trade zones across the country actively strengthened collaborative innovation, explored and promoted coordinated development, amplified the comprehensive effect of reform, and achieved positive results. For example, Beijing, Tianjin and Hebei Pilot Free Trade Zone established the Beijing-Tianjin-Hebei joint conference system, launched 153 items of "colleagues with the same standard" in government services, and implemented regional general office to serve the coordinated development of Beijing-Tianjin-Hebei. Shanghai, Jiangsu, Zhejiang and Anhui Pilot Free Trade Zones have established the Yangtze River Delta Pilot Free Trade Zone Alliance to create a mechanism for seeking common development, promoting innovation and sharing results, and achieved institutional innovation results in building a "single window" for international trade in the Yangtze River Delta and building an integrated oil and gas trading market. The Yellow River Basin Pilot Free Trade Zone Alliance will be established along the nine provinces of the Yellow River, and four cooperation mechanisms will be established, including "integrated construction" of social credit system, "integrated management of administrative examination and approval services", "integrated cooperation" of intellectual property protection and "integrated and smooth logistics and transportation services". Guangxi Pilot Free Trade Zone actively builds the most convenient seaport in the western region, effectively strengthens the connection with the backbone channels in southwest, northwest and central south, and serves the western development. Yunnan, Guangxi, Heilongjiang and other pilot free trade zones along the border plan to jointly promote the development and opening up along the border. The joint development of these pilot free trade zones has expanded the breadth and depth of institutional innovation, enriched the application scenarios of free trade policies, and expanded the dividend effect of free trade.It is of great significance for improving the efficiency of reform and innovation, serving to build a new development pattern, and effectively supporting the high-quality development of the free trade pilot zone.

　　Standing at a new starting point in ten years, the Pilot Free Trade Zone has ushered in new tasks. At the end of June this year, the State Council issued a document, taking the lead in conducting pilot projects in five qualified free trade pilot zones and Hainan Free Trade Port, such as Shanghai, Guangdong, Tianjin, Fujian and Beijing, connecting with international high-standard economic and trade rules, promoting institutional opening, and exploring ways for comprehensively deepening reform and opening up. The Ministry of Commerce will also work with relevant localities and departments to formulate a list of key tasks in the Pilot Free Trade Zone, clarify 164 key tasks to be independently promoted by the relevant pilot free trade zones in the next three years, further strengthen classified guidance, and promote the deepening of reform, practice and innovation in each pilot free trade zone according to local conditions.

　　Sharpen a sword for ten years and stride forward again. This year marks the tenth anniversary of the construction of China Pilot Free Trade Zone, and it is also the first year to implement the "strategy of upgrading the Pilot Free Trade Zone". On the new journey, on the basis of comprehensively summing up ten years’ construction experience, we should thoroughly implement the promotion strategy of the Pilot Free Trade Zone, carry out exploration in a wider field and at a deeper level, and strive to build a higher level pilot free trade zone. For example, we should speed up the pilot work of comprehensively docking international high-standard economic and trade rules, and further promote the institutional opening of rules, regulations, management and standards; Promote a reasonable reduction of the negative list of foreign investment in the Pilot Free Trade Zone, promote the introduction of a negative list of cross-border service trade, and lead the country to continue to expand and open up; Strengthen the overall planning and system integration of reform, thoroughly implement the upgrading strategy of the Pilot Free Trade Zone, and focus on launching a number of leading and integrated reform measures in key areas; Support their respective trade pilot zones to further deepen differentiated exploration and promote the innovative development of the whole industrial chain around key areas … … Let the seeds of institutional innovation in the Pilot Free Trade Zone take root and bear fruit nationwide, promote economic growth to rely more on innovation, and lead China’s high-quality economic development! (Yang Guangwang commentator Yu Qi)

Cctv newsVirus is a word that makes people turn pale and avoid it. However, there is such a scientist who, despite difficulties, has played a key role in successfully stopping the avian influenza epidemics such as H5N1 and H7N9 in China. She is Chen Hualan, director of the National Avian Influenza Reference Laboratory and academician of the Chinese Academy of Sciences.

The National Avian Influenza Reference Laboratory of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, which she led, built a safety "epidemic prevention wall" by relying on a number of international leading achievements independently developed, and contributed China’s wisdom and strength to the prevention of avian influenza in many countries around the world.

Where is the initial heart?

In 1999, as a postdoctoral fellow, Chen Hualan went to the Influenza Sub-center of the Centers for Disease Control (CDC) in the United States to conduct cooperative research on avian influenza. After the exchange, the other party kindly retained him, but Chen Hualan resolutely embarked on the road of returning home.

"It doesn’t matter if the conditions are backward, we can build it slowly." Chen Hualan said that China is a big country for raising poultry. Once bird flu breaks out, it will inevitably suffer great losses if it lacks effective means. "Since the knowledge and technology I have mastered are urgently needed by the country, why don’t I come back?"

Highly pathogenic avian influenza is a class A infectious disease. Once the bird flu epidemic is found all over the world, the common way is to cull all the poultry in a certain range. Doing so not only consumes huge human and financial resources, but also brings disaster to the aquaculture industry.

"Why not seek a better solution?" Chen Hualan, who has just returned to China, boldly proposed, "It is ‘ to develop a new and efficient vaccine for prevention and control; Four or two thousand catties ’ The best choice. " The laboratory she led was designated as the "National Reference Laboratory for Avian Influenza" by the Ministry of Agriculture, responsible for the epidemic diagnosis, epidemiological monitoring and prevention and control technology research of highly pathogenic avian influenza.

At the beginning of 2004, H5 subtype highly pathogenic avian influenza raided 14 provinces in China. The National Reference Laboratory for Avian Influenza receives samples from all over the country for final identification every day. In a short time, more than 50 cases of highly pathogenic H5N1 avian influenza were diagnosed, which played a key role in controlling the epidemic in time.　

Chen Hualan led the team to speed up the pace of vaccine research and development. In more than a year, they completed the research on the new avian influenza vaccine in the laboratory. The successful development of H5N1 and H5N1 avian influenza vaccines has greatly improved China’s ability to prevent and control avian influenza and saved tens of billions of yuan for the country.

Re-war virus

In March 2013, there were cases of human infection with H7N9 avian influenza in China. The rapid spread of the virus caused a lot of panic in the country and attracted great attention from the international community.

The epidemic situation is like military intelligence, and Chen Hualan has once again started a race against the virus. She and her colleagues sent a number of teams to take samples at the first time, and then immediately conducted research and analysis.

Less than 48 hours after the first infected case was announced, Chen Hualan’s team isolated a similar virus from the samples collected in the live poultry market. According to the research results, Chen Hualan suggested that the live poultry market in infected areas should be closed immediately. After her suggestion was adopted, the number of new infections decreased rapidly.

"Although the H7N9 virus that appeared in 2013 can infect people, it is not pathogenic to poultry, and chickens do not show any clinical symptoms after infection, which makes it difficult to find the virus in time." Chen Hualan later said.

The H7N9 avian influenza virus caused a total of 5 waves of human infections, resulting in 1,567 infections, of which more than 600 people were killed. From October every year to March the following year, it is a high incidence period of human infection with H7N9 avian influenza.

Chen Hualan said: "At the thought that H7N9 avian influenza virus is threatening the lives of thousands of people, we dare not relax for a moment."

In the four Spring Festival after the emergence of H7N9 virus, Chenhualan was spent in the laboratory. But the virus is a tough opponent.

"In January 2017, we found in the monitoring that the H7N9 avian influenza virus had a key mutation, and poultry began to get sick and died in large numbers after infection." The situation that Chen Hualan is most worried about has emerged. "The mutated virus is more harmful to people, and the mortality rate can reach more than 50%."

From January to September, 2017, the "race" between team Chen Hualan and the virus entered a sprint stage: intensify on-site sample collection and pathogen monitoring nationwide, speed up virus analysis and research, formulate prevention and control measures, put forward prevention and control suggestions, speed up the process of creating efficient vaccines, and accept evaluation and testing & HELIP; … Miracle happened like this. Before the arrival of the virus epidemic season in autumn and winter of 2017, Chen Hualan team successfully launched the bivalent inactivated vaccine of recombinant avian influenza virus (H5/H7).

The popularization of the vaccine has effectively controlled the spread of H7N9 avian influenza virus in poultry and successfully blocked the infection of H7N9 avian influenza virus in people.

be as usual

Behind the first-class scientific research is the unimaginable contribution of ordinary people. Team Chen Hualan conducts large-scale avian influenza virus monitoring twice a year, and members go to farms and live poultry markets across the country to take samples from live poultry and bring them back for analysis. When sampling, researchers should use swabs to take samples from the deep throat and cloaca of chickens respectively. In 2017 alone, the team members sampled 53,000 copies. After returning to the laboratory, they must isolate the virus as soon as possible and do further analysis and research.

In addition to epidemic diagnosis and vaccine research, Chen Hualan also led the team to strengthen the active surveillance of avian influenza epidemiology in China and explore the biological characteristics of the virus. By giving full play to the individual strengths of team members, a full chain and systematic influenza research layout has been formed. At the same time, it shoulders the responsibility of providing scientific reference for the prevention and control of bird flu epidemic and early warning of human influenza.

In 2013, Chen Hualan was selected as one of the top ten scientific figures in Nature, and Nature called her "the one fighting in the front line ‘ Influenza detective ’ " . In 2016, Chen Hualan won the "World Outstanding Female Scientist Achievement Award" awarded by UNESCO.

Even though Chen Hualan has stood in the leading position in the world, he and his team are always in a state of "preparing for war". Chen Hualan said: "Avian influenza virus can infect not only poultry, but also migratory birds. Migratory birds who migrate across borders are very free, and they don’t need to fly to any country ‘ Passport ’ . If they carry the virus, an epidemic may occur as soon as they come into contact with local poultry. We must always be vigilant and respond to emerging epidemics at any time. "

Now, the word "avian influenza" has quietly faded out of the sight of ordinary people, while Chen Hualan remains vigilant. "The highly pathogenic avian influenza virus has evolved rapidly, and we can’t relax at all". Some people ask, is it worthwhile to give up many pleasures in life for work? Chen Hualan replied slowly: "Is it more fun and worthwhile for researchers engaged in the prevention and control of infectious diseases to nip the highly dangerous bird flu epidemic in the bud?" (Text/Kan Chunyu)

　　[Global Network Reporter Li Dongyu] "Although I don’t drink, I always prefer American wine to French wine." On July 26, local time, when Trump once again issued a tariff threat to French-made wines, he used this sentence to express his support for domestic wines.

　　As a response to France’s recent announcement to levy a digital service tax on global technology giants, according to The New York Times, Trump first said on Twitter on the 26th, "France has just imposed a digital tax on our great American technology companies. If someone wants to tax them, it should also be their motherland — — America. "

　　Then, he added, "We will soon announce substantive reciprocal action against Macron’s foolish behavior."

　　Interestingly, Trump did not explicitly say what to do, but then meaningfully threw out a sentence, "I have always said that American wine is better than French wine!"

　　The New York Times said that shortly afterwards, Trump made another speech at the White House that day, further expounding the threat to France, saying that the French tax was "wrong" and his government was studying a possible wine tax. Trump told reporters, "Although I don’t drink, I always prefer American wine to French wine."

　　The New York Times said that this week, French President Macron signed a bill to impose a new digital tax on technology giants, and global Internet giants such as Facebook, Google and Amazon became potential targets. The tax rate is as high as 3%. The US Consumer News and Business Channel (CNBC) said that the Trump administration subsequently launched the 301 investigation under the Trade Act of 1974.

　　CNBC said that if after the investigation, the United States determines that this new tax is discriminatory or unreasonably targeted at American companies, Trump may respond with tariffs. Trade experts believe that Trump’s most likely response is to the French iconic product — — There is a 100% (import) tariff on wine.

　　"The Trump administration has always stated that it will not stand by and tolerate discrimination against American companies." This is what White House spokesman Judd Deere said in a statement on the 26th local time. The statement criticized France’s tax policy, but did not give any new details about what retaliatory measures the United States might take. Deere said that the government is "closely watching all other policy tools" except the investigation, so as to decide how to respond to France.

　　In the face of the tough stance of the United States, according to Agence France-Presse reported on 26th, French Economy Minister lemerre once said that Paris was not scared. "A universal tax on digital activities is a challenge for all of us. We hope to reach an agreement within the G7 and the OECD. At the same time, France will implement its own national decisions. "

　　Yang Guangwang Harbin April 25 th news (Reporter Pang Wei)April 25th is the National Child Vaccination Day.,This year’s publicity theme is "vaccination, disease prevention and control, health protection, life protection". Vaccination is the most economical and effective measure to prevent and control infectious diseases.,To this end,Heilongjiang ProvinceProvincial CDCPublish 61 articlesCommon knowledge of vaccinationquestions and answers.

Data Map Source: vision china

　　1 Q: What is a vaccine?

　　A: It refers to the preventive biological products used for human immunization in order to prevent and control the occurrence and epidemic of diseases, including immunization planning vaccines and non-immunization planning vaccines.

　　Q: What is an EPI vaccine?

　　A: It refers to the vaccines that residents should be vaccinated according to government regulations, including those determined by the national immunization program, those added by the people’s governments of provinces, autonomous regions and municipalities directly under the Central Government when implementing the national immunization program, and those used by the people’s governments at or above the county level or their health authorities for emergency vaccination or mass vaccination.

　　Q: What is a non-EPI vaccine?

　　A: It refers to other vaccines voluntarily vaccinated by residents.

　　Q: What is a vaccine marketing license holder?

　　A: It refers to an enterprise that has obtained the registration certificate of vaccine drugs and the drug production license according to law.

　　Q: What is immunization program?

　　A: Immunization planning refers to the plans, plans and strategies formulated by using effective vaccines to vaccinate susceptible people according to the national infectious disease prevention and control plan, and to vaccinate people in a planned way according to the vaccine varieties, immunization procedures or vaccination programs determined by the state or provinces, autonomous regions and municipalities directly under the Central Government, so as to prevent and control the occurrence and prevalence of specific infectious diseases, and to improve people’s health level and health civilization level through the implementation of national immunization planning.

　　Q: What kind of immunization planning system does the country implement?

　　A: Residents living in China have the right to be vaccinated with EPI according to law and fulfill their obligations to be vaccinated with EPI. The government provides free immunization program vaccines to residents. The people’s governments at or above the county level and their relevant departments shall ensure that school-age children are vaccinated with immunization programs. The guardian shall ensure that school-age children are vaccinated with EPI vaccine on time according to law.

　　7 Q: What are the immunization program vaccines for school-age children in our province?

　　A: At present, the immunization programs for school-age children in our province include hepatitis B vaccine, BCG vaccine, inactivated polio vaccine, live attenuated polio vaccine, DTP vaccine, measles vaccine, live attenuated hepatitis A vaccine, live attenuated Japanese encephalitis vaccine, group A meningococcal polysaccharide vaccine and group A+C meningococcal polysaccharide vaccine.

　　Q: What is routine vaccination?

　　Answer: It refers to the vaccination service provided by the vaccination unit for the vaccinated object within a relatively fixed vaccination service cycle time in accordance with the national immunization program, vaccine use guidelines and vaccine use instructions.

　　Q: What is mass vaccination?

　　A: It refers to the organized and centralized vaccination activities for a specific group of people who may be threatened by an infectious disease within a specific scope and time. Supplementary immunization (formerly called "booster immunization") is a commonly used form of mass vaccination.

　　Q: What is emergency vaccination?

　　Answer: When the epidemic situation of infectious diseases begins or has an epidemic trend, vaccination activities are carried out for the target population in order to control the spread of infectious diseases.

　　Q: Why can vaccination prevent diseases?

　　A: Scientific research shows that when bacteria or viruses invade the human body, the body will produce a substance that resists the bacteria or viruses. This substance is called antibody. Different bacteria or viruses will produce different antibodies, which are called specific antibodies. After recovery, this specific antibody still remains in the body. If the corresponding bacteria or viruses invade the body again, this specific antibody can protect the body from these bacteria or viruses. Vaccination is to artificially inoculate a small amount of bacteria or viruses and their metabolites after being attenuated or inactivated, so that the body can produce specific antibodies or cellular immune responses, thus producing resistance against this pathogen.

　　Q: Why do you have to take vaccination according to the immunization program?

　　A: Different vaccines have different immunization procedures, which are based on clinical trials and years of scientific practice. Such as hepatitis B vaccine, pertussis-diphtheria-tetanus combined vaccine, polio vaccine, etc., at least three doses of vaccination are needed to make children have sufficient immunity. As children grow up, the immunity acquired by vaccination in the body will gradually decline. Therefore, some vaccines need to be strengthened.

　　Q: Can different vaccines be vaccinated at the same time?

　　A: Two or more injectable vaccines should be inoculated in different parts. It is forbidden to mix two or more vaccines and inhale them into the same syringe for inoculation. At present, all the vaccines in the national immunization program can be vaccinated at the same time according to the immunization procedure or the principle of replanting. Immunization planning vaccine and non-immunization planning vaccine can be vaccinated at the same time. If you choose not to vaccinate at the same time, priority should be given to ensuring immunization planning vaccine vaccination.

　　Q: How long does it take for different vaccines not to be vaccinated at the same time?

　　A: If two or more live attenuated vaccines for injection are not vaccinated at the same time, they should be vaccinated at an interval of ≥28 days. Inactivated vaccine and oral attenuated live vaccine, if they are not inoculated at the same time with other kinds of vaccines (including attenuated and inactivated), there is no restriction on the inoculation interval.

　　Q: How do migrant children get vaccinated?

　　A: In China, the vaccination of floating children is managed locally (that is, where they live), and floating children enjoy the same vaccination services as local children. If children under 6 years old move to other cities (regions) and counties (districts), they can directly carry the vaccination certificate issued by the health department of their original place of residence to the vaccination unit where they live now. If the vaccination certificate has not been handled before or is lost, the vaccination certificate can be reissued at the vaccination unit in the current residence.

　　Q: Which is better, imported vaccine or domestic vaccine?

　　A: Both domestic and imported vaccines have strict quality control systems to ensure the safety and effectiveness of vaccines. There is no obvious difference in performance between domestic vaccines and imported vaccines. No matter domestic or imported vaccines, all vaccines will have a certain level of adverse reactions, and there is no obvious difference in the level of adverse reactions between imported vaccines and domestic vaccines. Compared with domestic vaccines, imported vaccines have higher investment in R&D, and there is a certain gap between the prices of imported vaccines and domestic vaccines due to factors such as tariffs, freight and marketing costs. The choice of domestic vaccine or imported vaccine depends on the importance that individuals attach to the performance and price of the vaccine. If economic conditions permit, you can choose to vaccinate imported vaccines at your own expense, but if you consider the cost performance, it is also good to choose domestic vaccines. Don’t fall into the misunderstanding that the higher the price, the better.

　　Q: Why should BCG be vaccinated at birth?

　　Answer: After inoculation with BCG, the body can have specific immunity to Mycobacterium tuberculosis, which can prevent the reproduction and spread of Mycobacterium tuberculosis in the human body, so it has a good effect on preventing tuberculous meningitis and miliary tuberculosis. The World Health Organization suggests that newborns should be vaccinated with BCG as soon as possible in areas with high and moderate tuberculosis prevalence. China’s immunization program is to vaccinate newborns with one dose of BCG at birth.

　　Q: Why should newborns be vaccinated with hepatitis B vaccine within 24 hours after birth?

　　A: Most carriers of hepatitis B virus surface antigen in China come from vertical transmission from mother to child and early childhood infection. Because newborns have no immunity to hepatitis B virus and their immune function is not perfect, once they are infected with hepatitis B virus, they will easily become carriers of hepatitis B virus surface antigen. After infants less than one year old are infected with hepatitis B virus, more than 90% of them will become chronic hepatitis B virus surface antigen carriers. Thus, it is particularly important for newborns to prevent hepatitis B. All newborns should be vaccinated with the first dose of hepatitis B vaccine as soon as possible within 24 hours after birth, and complete the whole course of three doses of hepatitis B vaccine according to the immunization program of 0, 1 and 6 months old.

　　Q: Is it necessary to strengthen immunization after the whole vaccination of hepatitis B vaccine is completed?

　　A: At present, neither the World Health Organization nor China advocates the complete vaccination of hepatitis B vaccine and the booster immunization after successful immunization. This is because: after the successful initial immunization of hepatitis B vaccine, the immune persistence is good. According to domestic observation, the protection rate is still as high as 88.6% 15 years after vaccination. After natural exposure to hepatitis B virus (HBV), the memory B lymphocytes of successful immunization recipients inoculated with hepatitis B vaccine can rapidly proliferate, differentiate and produce specific antibodies after being attacked by HBV. It has been proved that humoral immune memory reaction still exists even among immunocompetents with low antibody or no antibody after 5 years. There is cellular immunity, and it has been observed that there is also specific cellular immune memory in addition to humoral immune memory response after vaccination with hepatitis B vaccine. Under the protection of hepatitis B vaccine, children can safely pass through the high-risk period of HBV infection (1 ~ 3 years old) without strengthening immunization, and with the function of immune barrier, the chances of infection of immunized children are greatly reduced. However, high-risk groups (such as hemodialysis patients, medical staff, etc.) should be tested for antibodies every 6 ~ 12 months, and when anti-HBS is less than 10 miu/ml, intensive vaccination can be carried out.

　　Q: How long will it take to have antibodies after hepatitis B vaccination? How long can it be protected?

　　A: Vaccination with hepatitis B vaccine is the most effective measure to prevent HBV infection. The effective component of hepatitis B vaccine is HBsAg, which induces human body to produce anti -HBs (hepatitis B surface antibody) and plays a role. After the first vaccination, most anti -HBs were still negative or below the lower limit of detection value; Anti -HBs turned positive about 1 week after the second injection, that is, it was immune to HBV 35-40 days after the start of inoculation; Inoculation with the third dose can significantly increase the level of anti -HBs and prolong the protection period. The positive conversion rate of anti -HBs is as high as 95%-100% after the whole vaccination of newborns, and the protection period can reach more than 22 years. After the human body actively produces anti -HBs, it has immune memory. Even if the anti -HBs turns negative and is exposed to HBV again, the body can produce anti -HBs in a short time. Therefore, it is not necessary for non-high-risk people to strengthen hepatitis B vaccination.

　　Q: What should adults do if they don’t produce antibodies after hepatitis B vaccination?

　　Answer: For those who fail to respond after three doses of hepatitis B vaccine, they can be vaccinated with one dose of 60μg or three doses of 20μg hepatitis B vaccine, and their serum anti -HBs will be detected 1-2 months after the second dose of hepatitis B vaccine. If there is still no response, they can be vaccinated with one dose of 60μg recombinant yeast hepatitis B vaccine.

　　Q: Can newborns of pregnant women infected with hepatitis B virus (HBV) breastfeed?

　　A: Although HBsAg and HBV DNA can be detected in the milk of pregnant women infected with hepatitis B virus, and some scholars believe that chapped nipples, excessive sucking of infants and even biting of nipples may transmit the virus to infants, these are theoretical analysis and lack of evidence-based medical evidence. Even without immunization, the infection rate of breast-fed and artificially fed newborns is almost the same. More evidence proves that even if pregnant women are HBeAg positive, breastfeeding does not increase the risk of infection. Therefore, after formal prevention, whether pregnant women are HBsAg positive or negative, their newborns can breastfeed, and there is no need to test whether there is HBV DNA in the milk.

　　Q: What should medical staff and others who accidentally expose hepatitis B virus do?

　　Answer: (1) Squeeze gently around the wound to discharge the blood in the wound, then rinse the wound with 0.9%NaCl solution, and then treat it with disinfectant. (2) HBV DNA and HBsAg should be detected immediately and rechecked after 3-6 months. (3) Those who have been vaccinated with hepatitis B vaccine and are known to be positive for anti -HBs (anti -HBs≥10mIU/ml) may not be treated. If you have not been vaccinated with hepatitis B vaccine, or if you have been vaccinated with hepatitis B vaccine, but the anti -HBs is less than 10 miu/ml or the anti-HBS is unknown, you should immediately inject 200-400 IU of HBIG, and at the same time, inoculate one dose of hepatitis B vaccine (20μg) in different parts, and then inoculate the second and third doses of hepatitis B vaccine (20μg) one month and six months later, respectively.

　　Q: Why should I stay on observation for at least 30 minutes after vaccination?

　　A: After vaccination, due to individual reasons, very few people may have allergic reactions. Monitoring data show that anaphylactic shock mostly occurs within 30 minutes after inoculation. After anaphylactic shock, if it is not under the supervision of medical staff, it is easy to be life-threatening. Therefore, doctors and first-aid drugs must be equipped at the inoculation site, mainly to prevent accidents. If the guardian suspects that his child has an adverse reaction to vaccination, he should consult or report to the vaccinator or the Center for Disease Control and Prevention in time.

　　Q: What is a suspected adverse reaction to vaccination?

　　A: It refers to the reaction or event that is suspected to be related to vaccination after vaccination.

　　Q: What are the classifications of suspected adverse reactions to vaccination?

　　A: It includes adverse reactions (general reactions and abnormal reactions), vaccine quality accidents, vaccination accidents, coupling diseases and psychogenic reactions.

　　Q: What are the conditions that do not belong to the abnormal reaction of vaccination?

　　A: The abnormal reaction of vaccination refers to the adverse drug reaction caused by the qualified vaccine in the process of implementing the standardized vaccination or after implementing the standardized vaccination, and the relevant parties have no fault.

　　The following situations do not belong to the abnormal reaction of vaccination:

　　(a) the general reaction after vaccination caused by the characteristics of the vaccine itself;

　　(2) Damage caused to the recipients due to vaccine quality problems;

　　(three) the damage caused to the recipients by the vaccination unit’s violation of the vaccination work norms, immunization procedures, guiding principles for vaccine use, and vaccination programs;

　　(four) the recipient is in the incubation period or precursor period of a disease at the time of inoculation, and the disease is coupled after inoculation;

　　(5) The recipient has vaccination contraindications specified in the vaccine instructions, and the recipient or his guardian failed to truthfully provide the health status and vaccination contraindications of the recipient before vaccination, and the original disease of the recipient has an acute recurrence or aggravation after vaccination;

　　(6) Psychogenic reactions of individuals or groups due to psychological factors.

　　Q: Why do some recipients have redness and inflammation in the injection area after vaccination?

　　A: Red swelling is a manifestation of inflammation and a common phenomenon in vaccination. It is the body’s responsive response to various damaging stimuli. It is characterized by local tissue deterioration, exudation and proliferation. When vaccinating, injection is often used, which itself can stimulate the human body to cause minor trauma and cause inflammation; At the same time, the vaccine itself is a foreign body and has certain toxicity. The pH, osmotic pressure and preservatives contained in the vaccine can cause inflammatory reactions to varying degrees. In addition, the inoculation of live vaccine is essentially a mild artificial infection, which can not only cause a mild infection process similar to the virulence of the microorganism, but also be accompanied by inflammatory reaction.

　　From the immunological point of view, inflammatory reaction is caused by the interaction between antigen and antibody or sensitized lymphocytes, which leads to the release of various inflammatory mediators by cells or the activation of inflammatory mediators in plasma or tissue fluid. Although the inflammation caused by vaccination may cause damage to the recipients, it is also conducive to the exudation of complement and antibody in the blood and strengthen the defense function.

　　Q: How to deal with the general reaction after vaccination?

　　A: After vaccination, you should stay in the vaccination unit for at least 30 minutes. Some children will have some reactions after vaccination, such as low fever, local redness and swelling, and may be accompanied by general discomfort, such as burnout, loss of appetite and fatigue. The above symptoms usually last for 1 ~ 2 days and disappear without any treatment. Children who have the above reactions after vaccination should take a proper rest, drink plenty of boiled water and keep warm to prevent other diseases from secondary. If there is a serious reaction, you should seek medical advice in time.

　　Q: Can children with neonatal jaundice be vaccinated?

　　A: Jaundice is a common clinical symptom in neonatal period, which can be divided into two types: physiological jaundice and pathological jaundice.

　　Physiological jaundice refers to the newborn’s 2 ~ 3 days after birth, which first appears on the face and neck, and then spreads all over the skin of trunk and limbs, with slight yellow staining and yellow sclera, but the palms and soles are not yellow, and the blood bilirubin is less than 12 mg/L, which reaches its peak on the 4 ~ 6 days after birth. Full-term infants mostly subside within 7 ~ 10 days after birth, and premature infants can delay to the 3 ~ 4 weeks. Children with physiological jaundice, except jaundice, are in good health, without other clinical symptoms, have normal urine and stool color, do not need treatment, have a good prognosis, and can be vaccinated with various vaccines.

　　Pathological jaundice can be divided into infectious jaundice and non-infectious jaundice (hemolytic disease of newborn, biliary atresia, breast-feeding jaundice, genetic diseases and drug-induced jaundice). If neonatal jaundice occurs in one of the following situations, it should be considered whether it is pathological jaundice: jaundice occurs within 24 hours; The degree of jaundice is deep and progresses rapidly, exceeding 6 mg/d L； in one day; Blood bilirubin > 12 mg/l; Jaundice lasts more than 2 weeks or reappears after it subsides. Pathological jaundice is the manifestation of the disease, and it should be treated in time, and vaccination is not allowed.

　　Q: Can allergic constitution be vaccinated?

　　A: The so-called "allergic constitution" is not a contraindication for vaccination. Allergic reactions are mild and severe, and serious allergic reactions caused by vaccines are rare. Compared with the risk of illness without vaccination, the benefit of vaccination is greater. The so-called "allergic constitution" can be observed after vaccination. If there are allergic manifestations, they can be treated in time, which generally will not affect health (nor affect the vaccination effect). If you are seriously allergic to the known vaccine ingredients or have laryngeal edema, anaphylactic shock and other serious systemic allergic reactions due to vaccination in the past, it is forbidden to continue to vaccinate the same vaccine.

　　Q: What common diseases are not taboo for vaccination at present?

　　A: Physiological and breast-feeding jaundice, history of simple febrile convulsion, stable epilepsy control, congenital inherited metabolic diseases (congenital hypothyroidism, phenylketonuria, trisomy 21 syndrome, etc.), stable brain diseases, congenital heart disease, congenital infection (syphilis, cytomegalovirus and rubella virus), etc.

　　Q: Is it necessary to vaccinate Covid-19 vaccine?

　　A: It is necessary. On the one hand, most people in our country have no immunity against Covid-19, and they are susceptible to Covid-19. After the onset of infection, some people will develop into critical illness and even cause death. After vaccination, on the one hand, most people can gain immunity, thus effectively reducing the risk of illness, severe illness and death; On the other hand, through the orderly vaccination of Covid-19 vaccine, we can gradually establish an immune barrier among the population, stop the epidemic of COVID-19, and restore the normal operation of China’s social economy and residents’ life as soon as possible.

　　Q: How does Covid-19 vaccine work in human body?

　　A: After vaccination, the human body will produce protective antibodies, and some vaccines will also make the human body have cellular immunity and form corresponding immune memory. In this way, the human body has immunity against diseases. Once Covid-19 invades the human body, antibodies produced by vaccines and cytokines released by cellular immunity can identify, neutralize or kill the virus, and immune memory can quickly mobilize the immune system to play a role, so that the virus cannot continue to proliferate in the body, thus achieving the purpose of preventing diseases.

　　Q: At present, how many kinds of Covid-19 vaccines have been approved for conditional marketing or emergency use in China?

　　A: Covid-19 vaccines from five manufacturers in China have been approved for conditional marketing or emergency use. Among them, there are 3 inactivated vaccines and 1 adenovirus vector vaccine approved for marketing conditionally; In addition, one recombinant Covid-19 vaccine (CHO cells) was approved for emergency use.

　　Q: Who are the approved vaccine manufacturers in Covid-19?

　　A: The three Covid-19 inactivated vaccine products that have been conditionally approved for marketing are produced by Sinopharm China Bio-Beijing Institute of Biological Products (Beijing Institute), Wuhan Institute of Biological Products (Wuhan Institute) and Beijing Kexing Zhongwei Biotechnology Co., Ltd. (Kexing Zhongwei).

　　The adenovirus vector vaccine approved for marketing conditionally is produced by Kangxinuo Bio-stock Company (Kangxinuo).

　　The recombinant subunit vaccine approved for emergency use is produced by Anhui Zhifeilong Kema Biopharmaceutical Co., Ltd. (Zhifeilong Kema).

　　Q: At this stage, who is the target of Covid-19 vaccine?

　　A: The vaccination target of Covid-19 vaccine in China is people aged 18 and above.

　　Q: At present, how many doses of Covid-19 vaccine are required to be used in China? How long is the interval?

　　A: At present, Covid-19 inactivated vaccine needs to be inoculated with two doses; The interval between the first dose and the second dose should be 3 weeks or more, and the second dose should be completed as soon as possible within 8 weeks after the first dose.

　　Adenovirus vector vaccine needs 1 dose.

　　The recombinant subunit vaccine needs 3 doses; The interval between the first dose and the second dose, and the interval between the second dose and the third dose are suggested to be 4 weeks or more. The second dose should be completed within 8 weeks after the first dose and the third dose should be completed within 6 months after the first dose.

　　Q: Where can I get the Covid-19 vaccine?

　　A: Vaccination in Covid-19 is carried out in vaccination units approved by local health administrative departments. Usually, the inoculation unit is located in the health service center, township health center or general hospital in the jurisdiction. If vaccination involves some departments or enterprises with relatively concentrated key targets, some temporary vaccination units will be set up locally according to the situation.

　　The health administrative department or disease prevention and control institution in the jurisdiction will also announce the vaccination units that can carry out Covid-19 vaccination as required, including the location and service hours. Please pay attention to the relevant information release platform.

　　Q: What are the contraindications for COVID-19 vaccination?

　　A: The taboo of vaccination refers to the situation that vaccination should not be given. According to the Technical Guide for Vaccination in Covid-19 (First Edition), the common taboos for vaccination include: 1. Those who are allergic to the active ingredients, any inactive ingredients and substances used in the production process, or those who have been allergic to similar vaccines before; 2. Those who have had severe allergic reactions to vaccines in the past (such as acute allergic reactions, angioneurotic edema, dyspnea, etc.); 3. People with uncontrolled epilepsy and other serious nervous system diseases (such as transverse myelitis, guillain-barre syndrome, demyelinating diseases, etc.); 4. Those who are suffering from fever, or acute diseases, or acute attacks of chronic diseases, or patients with uncontrolled serious chronic diseases; 5. Pregnant women. Some taboos, such as fever, are temporary. When the situation that caused the taboo no longer exists, you can vaccinate later.

　　Q: How to find and grasp the taboo of vaccination?

　　A: During the operation, if the first dose of vaccine causes severe allergic reaction, and it cannot be ruled out that it is caused by the vaccine, it is not recommended to vaccinate the second dose. To understand the ingredients of the vaccine, people who have been allergic to the ingredients of the vaccine in the past cannot be vaccinated.

　　At the time of vaccination, the recipient should truthfully report the physical health status, disease history and allergy history to the vaccination doctor; The vaccination doctor will ask about the health status and past allergy history of the recipient.

　　Q: Can Covid-19 vaccines from different manufacturers replace vaccination?

　　A: According to the Technical Guide for Vaccination in Covid-19 (First Edition), it is suggested to complete the whole vaccination with inactivated Covid-19 vaccine from the same company at this stage. In case of special circumstances, such as the vaccine can’t continue to be supplied, the recipients are inoculated in different places, and the whole process of vaccination can’t be completed with the inactivated vaccine of Covid-19 from the same enterprise, the inactivated vaccine produced by other enterprises can be used to complete the vaccination.

　　Q: Where and how to vaccinate Covid-19 vaccine?

　　A: At present, the five Covid-19 vaccines have been approved for inoculation in deltoid muscle of upper arm, and the inoculation route is intramuscular injection.

　　Q: What should we pay attention to in the process of vaccination in Covid-19?

　　A: During the vaccination process, the recipients should pay attention to and cooperate with the following matters:

　　Before vaccination, you should know about COVID-19’s disease, Covid-19’s vaccine and vaccination process in advance.

　　When vaccinating, you need to bring relevant certificates (ID card, passport, etc.), do personal protection according to local prevention and control requirements, cooperate with the on-site vaccination staff to ask, and truthfully provide information such as my health status and vaccination contraindications.

　　After inoculation, you need to stay for 30 minutes; Keep the skin of the inoculated area clean and avoid scratching the inoculated area with your hands; If there is any suspected adverse reaction, report it to the inoculation unit and seek medical treatment in time if necessary.

　　Q: Why do you have to stay on observation for half an hour after vaccination?

　　A: After vaccination, very few people may have acute allergic reactions and syncope. Acute allergic reactions that seriously endanger life safety often occur within 30 minutes after vaccination. In case of acute allergic reaction, you can take timely treatment measures at the scene. Syncope also occurs mostly within half an hour after inoculation. If you leave the observation site immediately after inoculation, you may cause accidental injury to the recipient due to syncope. Therefore, the recipients need to stay in the designated area of the vaccination unit for half an hour after vaccination.

　　Q: Why do you need a certain interval between doses of inactivated vaccine in Covid-19?

　　A: Usually, inactivated vaccines need to be vaccinated several times to achieve better immune effect. According to the clinical trial data, the first dose of inactivated vaccine in COVID-19 can stimulate the body to produce partial immune response, and the second dose can produce better immune effect. The interval between doses generally needs to be determined according to the results of clinical trials. If two doses of inoculation are not completed within the time required by the program interval, replanting should be done as soon as possible.

　　Q: How to replant those who have not completed the whole immunization program? Do you need to start over?

　　Answer: For vaccines with two or three doses of immunization, those who have not been vaccinated in the whole process are advised to replant the unfinished doses as soon as possible, and there is no need to restart vaccination according to the immunization program.

　　Q: Do people whose interval between two doses of inactivated Covid-19 vaccine is less than 3 weeks need replanting?

　　Answer: For those who have completed two doses of inactivated vaccine in Covid-19 within 14 days, one dose of inactivated vaccine should be replanted as soon as possible three weeks after the second dose. For those who complete 2 doses of inactivated Covid-19 vaccine in 14-21 days, there is no need to replant.

　　Q: Is it necessary to strengthen immunization after the whole vaccination of inactivated vaccine in Covid-19 at this stage?

　　A: Strengthening immunization is not recommended at this stage.

　　Q: It was suggested that HPV vaccine and Covid-19 vaccine should not be vaccinated at the same time. How long should the interval be?

　　A: Covid-19 vaccine is a new vaccine. In order to identify or distinguish possible suspected adverse reactions of vaccine, it is not recommended to vaccinate Covid-19 vaccine together with other vaccines (including HPV vaccine) at present. However, it doesn’t mean that you can’t vaccinate other vaccines after Covid-19 vaccination, but it is suggested that Covid-19 vaccine and other vaccines should be vaccinated more than two weeks apart. It must be noted that when rabies vaccine, tetanus vaccine and immunoglobulin need to be vaccinated urgently due to animal injury, trauma and other reasons, the vaccination interval with Covid-19 vaccine may not be considered.

　　Q: Can women of childbearing age and lactation be vaccinated with Covid-19 vaccine?

　　A: If you are pregnant after vaccination or have been vaccinated in the case of unknown pregnancy, based on the understanding of vaccine safety, it is not recommended to take special medical measures (such as termination of pregnancy) just because you have been vaccinated with Covid-19 vaccine. It is recommended to do a good job in pregnancy examination and follow-up. For women who have a pregnancy plan, it is not necessary to delay the pregnancy plan just because of Covid-19 vaccination.

　　Although there is no clinical research data on the effect of Covid-19 vaccine on lactating infants, based on the understanding of vaccine safety, it is suggested to vaccinate lactating women (such as medical staff) who are at high risk of Covid-19 infection. Considering the importance of breast-feeding for infants’ nutrition and health, and referring to the international practice, it is suggested that breast-feeding should be continued after breast-feeding women are vaccinated with Covid-19 vaccine.

　　Q: Can people aged 60 and above be vaccinated with Covid-19 vaccine?

　　A: People aged 60 and above are at high risk of severe illness and death after being infected with Covid-19. At present, the number of four phase III clinical trials of Covid-19 vaccine approved for marketing is limited, and the phase III trial of recombinant subunit vaccine is still in progress, and there is no data on the protective efficacy of the vaccine for this population. However, the data of the above-mentioned phase I/II clinical study of the vaccine show that the vaccination safety of this population is good. Compared with the population aged 18-59, the titer of neutralizing antibody after vaccination is slightly lower, but the positive conversion rate of neutralizing antibody is similar, suggesting that the vaccine will also have a certain protective effect on people over 60 years old, so vaccination is recommended.

　　Q: Can people with chronic diseases be vaccinated with Covid-19 vaccine?

　　A: People with chronic diseases are people with high risk of severe illness and death after being infected with Covid-19. People with chronic diseases with stable health and good drug control should not be considered as the taboo population for vaccination in Covid-19, so vaccination is recommended.

　　Q: Can people with impaired immune function be vaccinated with Covid-19 vaccine?

　　A: People with impaired immune function are people with high risk of severe illness and death after Covid-19 infection. At present, there is no data on the safety and effectiveness of Covid-19 vaccine for this population (such as malignant tumor, nephrotic syndrome, AIDS patients) and human immunodeficiency virus (HIV) infected people. The immune response and protective effect of this group of people may be reduced after vaccination. For inactivated vaccine and recombinant subunit vaccine, according to the safety characteristics of the same type of vaccine in the past, vaccination is recommended; For adenovirus vector vaccine, although the vector virus used is replication-deficient, there is no safety data of the same type of vaccine in the past. It is recommended to vaccinate after being fully informed that the benefits outweigh the risks.

　　Q: Do I need to get Covid-19 vaccine if I have been infected with Covid-19?

　　A: The existing research data show that it is rare to get reinfected in Covid-19 within 6 months after infection. Previous COVID-19 virus-infected people (patients or asymptomatic infected people) can receive one dose after 6 months on the basis of full notification.

　　Q: How long will it take to produce antibodies against Covid-19 after Covid-19 inactivated vaccine is inoculated?

　　A: According to the previous clinical trial of inactivated vaccine in Covid-19, the vaccinated population can have a good immune effect about two weeks after the second dose of inactivated vaccine is inoculated.

　　Q: Is it necessary to test antibodies before and after vaccination?

　　A: There is no need to carry out Covid-19 nucleic acid and antibody testing before vaccination; Routine antibody detection after vaccination is not recommended as the basis for successful immunization.

　　Q: Do I still need to do nucleic acid testing after Covid-19 vaccination? Can vaccination certificate replace nucleic acid test report?

　　Answer: After vaccination with Covid-19 vaccine, a very small number of the recipients still have positive nucleic acid test or illness due to protection failure: 1. After the whole vaccination, some people failed to get effective protection due to immune failure. After exposure to Covid-19, this group of people may be infected with Covid-19 and have positive nucleic acid test or illness. 2. It takes some time to produce protective effect after vaccination. If you are infected with Covid-19 during this period, you may detect nucleic acid positive or get sick. 3. Patients who are in the incubation period of the disease or asymptomatic infected people may still detect nucleic acid positive or get sick because they have been infected even after vaccination.

　　These people may become infected persons. When the prevention and control of epidemic situation in COVID-19 needs to be screened for nucleic acid, Covid-19 vaccination certificate cannot replace the nucleic acid test report, and it is necessary to cooperate with relevant departments to carry out nucleic acid test.

　　Q: After the mutation in Covid-19, is Covid-19 vaccine still effective?

　　A: According to the global monitoring of Covid-19 mutation, there is no evidence that virus mutation will invalidate the existing Covid-19 vaccine. Virus is one of the simplest organisms, and its proliferation depends on living cells. In the process of proliferation, the virus will mutate. The World Health Organization, research institutions in various countries, vaccine manufacturers, etc. are paying close attention to the mutation situation in Covid-19, and are also carrying out related research, which will provide early warning and scientific analysis basis for the follow-up vaccine development and application.

　　Q: What are the common adverse reactions of vaccination in Covid-19?

　　A: According to the results of the previous clinical trial of Covid-19 vaccine and the information collected during emergency use, the common adverse reactions of Covid-19 vaccine in China are basically similar to those of other vaccines that have been widely used. Common adverse reactions are mainly manifested as redness, induration and pain at the inoculation site, as well as clinical manifestations such as fever, fatigue, nausea, headache and muscle soreness. Relevant departments will continue to strengthen the real-time monitoring and evaluation of adverse reactions.

　　Q: Will our prevention and control measures be adjusted after vaccination in COVID-19?

　　A: For individuals, the protective effect of vaccination is not 100%, and it takes some time to produce protective antibodies. For the population, Covid-19 is still easy to spread without forming an immune barrier. Therefore, in order to prevent the COVID-19 epidemic from rebounding, some prevention and control measures should still be adhered to at this stage, including wearing masks, keeping social distance, washing hands frequently, ventilation and other protective measures. The prevention and control measures for COVID-19 epidemic will be adjusted in time with the improvement of vaccine coverage rate in COVID-19 and the change of epidemic situation at home and abroad.

　　The Fifth Plenary Session of the 18th Central Committee of the Communist Party of China (CPC) was held in Beijing from October 26th to 29th, 2015, and General Secretary of the Supreme Leader made an important speech. The plenary session stressed that to achieve the development goals during the Thirteenth Five-Year Plan period, we must firmly establish and earnestly implement the development concept of innovation, coordination, green, openness and sharing.

　　This year is an important year for the implementation of the 13 th Five-Year Plan and the deepening of supply-side structural reform.

　　Whether the development goals of the "Thirteenth Five-Year Plan" can be achieved, there are 10 words that are crucial — — Five development concepts of "innovation, coordination, green, openness and sharing".

　　How important are the five development concepts for the current and future development of China? According to the Supreme Leader, the new development concept is baton and traffic light, which embodies the development ideas, development direction and development focus of China in the "Thirteenth Five-Year Plan" and even in a longer period.

　　Since the 18th National Congress of the Communist Party of China, the five development concepts have run through the economic and social development of China, and have really influenced our lives.

　　Advocating innovation: "China artifact" swipes the screen network, which has greatly improved my country.

　　In recent years, China’s economic growth has slowed down and its development has entered a "new normal", but some people think that China’s economy is dying! In response to this question, the attitude of the supreme leader is very clear. "I have firm confidence in the sustained and healthy development of China’s economy." At the same time, he also gave a "prescription" for the problems in development: the fundamental way out for China’s economic development to break through the bottleneck and solve deep-seated contradictions and problems lies in innovation.

　　How effective has this medicine been in the past five years? For ordinary people, the China artifacts that have been swiped on the Internet may have the deepest feelings: Beidou, the world’s most accurate navigation satellite system; Tiangong-2, the first real space laboratory; the world’s fastest supercomputer, Shenwei Light of Taihu Lake; Mozi, the world’s first quantum science experimental satellite; C919, a large domestic aircraft with international mainstream standards; and advanced world level. …

　　When we sigh "awesome, my country" again and again, we really feel the "welfare" brought by innovation and development. People in China who have these "artifacts" have a more convenient life, a more secure life and a harder waist abroad!

　　In the ranking of global innovation index published by the World Intellectual Property Organization in 2017, China rose from 35th in 2013 to 22nd, ranking first among middle-income economies.

　　Whether China’s economy will work or not, don’t fight a war of words, just prove it to you with tangible innovation achievements!

　　Pay attention to coordination: a well-off society in an all-round way is indispensable, and the promise to the people must be fulfilled.

　　In history, there are many examples of countries falling into a "trap" and stagnating because of unbalanced development. After China’s economic development has entered the "new normal", all kinds of speculations and worries about the "middle income trap" are rampant!

　　Undeniably, there are some unbalanced problems in the development of China, for example, in some places, "cities are like Europe, and rural areas are like Africa", and in some places, people are "pocketed and empty-headed" and so on. The proposal of coordinated development is an effective way to face up to and solve problems.

　　In the past five years, many achievements in the coordinated development of regions, urban and rural areas, economy and society can be personally experienced by ordinary people: the construction of rural teachers has been placed in a strategic position of giving priority to development, benefiting more than 3.3 million rural teachers and more than 40 million rural students; More than 31 provinces have introduced implementation plans for household registration system reform, and generally proposed to cancel the distinction between agricultural registered permanent residence and non-agricultural registered permanent residence and relax restrictions on settlement; The reimbursement rate of medical insurance for employees and residents is above 80% and 50% respectively … …

　　Coordinated development is not only to avoid falling into the trap, but also a solemn commitment made by the party to the people — — Build a well-off society in an all-round way by 2020. I believe that as long as we implement the concept of coordinated development and make up the weak areas, weak areas and weak links, an all-round well-off society will be realized as scheduled.

　　Advocating Green: "Lucid waters and lush mountains are invaluable assets" has become the consensus of the whole people.

　　While China has become the second largest economy in the world, the deteriorating ecological environment has also become the biggest "worry" for the people.

　　For economic growth, sacrifice the environment and ecology! For Jinshan Yinshan, I lost green mountains and green hills! This "GDP-only" development concept will never be agreed by ordinary people.

　　The supreme leader saw the crux of the problem and decisively put forward that "it is better to have green mountains and green hills than Jinshan Yinshan".

　　On the one hand, we will remove the curse from leading cadres at all levels. "Even if the GDP slips to the seventh and eighth places, it has made progress in green development and contributed to controlling air pollution and solving smog, then you can hang red flowers and be a hero."

　　On the other hand, the central environmental protection inspector has covered 23 provinces, put 1,183 cases on file for investigation, detained 1,103 people and held 11,390 people accountable.

　　Although, there is still a long way to go to solve environmental problems. But fortunately, after five years of hard work, the concept of "Lucid waters and lush mountains are invaluable assets" has become the consensus of the whole people. As long as China society continues to exert its strength from top to bottom, the "beautiful China" with clear sky and clear water will not be far away.

　　Thick planting and opening up: China has gained consensus and won respect in the international community

　　Nearly 40 years of reform and opening up, China’s social outlook, people’s living standards and international status … … Have undergone earth-shaking changes. And the occurrence of this series of changes, as the supreme leader said, "depends on unremitting efforts to promote reform and opening up."

　　How much does reform and opening up weigh in the hearts of the supreme leader? After taking office as general secretary, he left Beijing for his first inspection tour and came to Guangdong. At that time, he clearly pointed out that "reform will not stop and opening up will not stop". In the past five years, from the implementation of the FTZ strategy to the construction of the Belt and Road Initiative, from the G20 Hangzhou Summit to the upcoming meeting of BRICS leaders in Xiamen, from becoming one of the largest foreign investors in the world to China, which has contributed over 30% to the world economic growth annually and is already the "first engine of world economic growth", the pace of opening up has never stopped.

　　Adhering to the concept of open development has also enabled China to gain consensus and win respect in the international community. After the Belt and Road Initiative was launched, more than 100 countries (regions) and international organizations expressed their active support and participation, and 40 countries and international organizations signed cooperation agreements with China.

　　China’s opening to the outside world does not seek hegemony or expansion, but seeks win-win cooperation. At the same time of its rapid development, it has also provided development opportunities for all countries in the world and promoted world economic growth.

　　Promote sharing: strive to turn the "concern" of ordinary people into reality.

　　"Sense of gain" is a word that people are very concerned about now. The working class is concerned about whether the salary can be higher, the retirees are concerned about whether the pension can be higher, and the rural people are concerned about whether the income gap with the city people can be smaller … …

　　In fact, these are not only the concerns of ordinary people, but also the concerns of the CPC Central Committee.

　　In the past five years, the CPC Central Committee with the Supreme Leader as the core has never forgotten the solemn commitment of "making people have more sense of reform" and strived to turn the "care" of the people into reality: in 2016, the per capita disposable income of the national residents increased by 44.3% compared with 2012; Pensions have achieved "twelve consecutive rises"; The income gap between urban and rural residents has dropped to about 2.8 times; The rural poor population is decreasing by more than 10 million people every year … …

　　China’s economic development has achieved today’s achievements thanks to more than 1.3 billion people, and the fruits of development should be shared by more than 1.3 billion people. In the future, whether it is to build a well-off society in an all-round way or to realize the great rejuvenation of the nation, it is inseparable from the support of the concept of shared development.

　　In the past five years, China has solved many problems through development, but it still faces some problems. The five development concepts are put forward in view of the outstanding contradictions and problems in China’s development. Unswervingly implementing the five development concepts will surely lead China to approach the goal of national rejuvenation step by step and step by step to the center of the world stage.

　　Recently, respiratory diseases have been high.

　　"Syncytial virus" topped the hot search list.

　　Some netizens asked questions.

　　"What is this?"

　　Syncytial virus is not a new respiratory disease.

　　Syncytial virus is not a new respiratory disease, and there was an anti-seasonal epidemic this summer.

　　Tang Zhichao, deputy director of the Department of Disease Control, Shunyi Women and Children Hospital, Beijing Children’s Hospital, said that respiratory syncytial virus is the most important virus pathogen that causes acute lower respiratory infection in children under 5 years old worldwide. Respiratory syncytial virus (RSV) infection is the primary cause of hospitalization of infants with viral respiratory infection, which seriously harms children’s health, especially premature infants and infants with congenital heart disease or primary immunodeficiency.

　　Children and adults can be infected.

　　Source: Yangguang. com

　　Syncytial virus is an RNA virus, which is transmitted by droplets and close contact, or by contaminated hands and objects. Patients often have upper respiratory symptoms after infection.

　　The incubation period of syncytial virus is usually 2-8.
Days, detoxification can last for 1-3 weeks. Early infection is mostly confined to the upper respiratory tract, showing symptoms of upper respiratory tract such as nasal congestion, runny nose, cough and hoarseness.

　　The typical symptoms of children infected with syncytial virus are fever, cough, stuffy nose and runny nose.

　　The typical symptoms of adult infection are very similar to the common cold, such as low-grade fever, cough, stuffy nose and runny nose.

　　Most patients’ symptoms will disappear spontaneously within 1-2 weeks, and a small number can develop into lower respiratory tract infection (i.e. bronchiolitis or pneumonia), which is more common in young infants. Clinical symptoms include cough and wheezing.

　　Gao Weiwei, chief physician of neonatal respiratory department of Guangdong Maternal and Child Health Hospital, said that syncytial virus is about 2.5 times as contagious as influenza.

　　At present, there are no syncytial virus vaccines and special therapeutic drugs on the market in China. Syncytial virus can be repeatedly infected and easily spread at home. In the absence of vaccines and effective drugs, measures such as strengthening personal protection should be taken to prevent infection.

　　The doctor reminds: Don’t overdo it and don’t "mix and match".

　　Recently, Xiao Zhao, a 16-year-old high school student, was admitted to the emergency intensive care unit for taking four kinds of cold medicines. Xiao Zhao found that she had symptoms of a cold and a little fever, so she took ibuprofen and crack at the same time. After taking the medicine, he felt that his symptoms were not obviously relieved, so he added two other cold medicines, which is equivalent to taking four cold medicines together.

　　Source: CCTV News

　　Gan Yongxiong, Chief Physician of Emergency Intensive Care Unit of Fangqiao Campus of the First Affiliated Hospital of Ningbo University: After being sent to the hospital, after our doctor’s judgment, we finally made it clear that it was acute renal failure and rhabdomyolysis, which was the effect of the superposition of these cold medicines on the kidneys.

　　The doctor reminded not to take too much medicine and not to "mix and match". Patients should pay attention to the drug instructions when taking drugs by themselves, and should not increase or decrease the types and doses of drugs at will. Even if you only take one drug, you can’t increase or decrease the dose at will. If multiple drugs need to be taken at the same time, it is best to consult a doctor in advance and take them according to the doctor’s advice. If you accidentally take too much medicine and cause discomfort, you should seek medical advice in time, inform the doctor in detail about the recent medication, and actively cooperate with the treatment.

　　In view of the recent increase in the number of outpatient and emergency departments in some places and the increase in the number of children infected with respiratory diseases, the responsible comrades of the National Health and Wellness Commission answered questions of concern to some people, especially the families of children, in an interview on November 23.

　　Q:

　　Recently, many local children’s specialized hospitals are overcrowded. What measures has National Health Commission taken to relieve them?

　　A:

　　Recently, we have continued to pay attention to the diagnosis and treatment of children susceptible to infectious diseases during the high incidence period, and guided all localities to strengthen overall planning and implement a graded diagnosis and treatment system.

　　Q:

　　Some community hospitals have recently set up inspection services for children, but some parents are worried that the lack of diagnosis and treatment capacity in community hospitals will delay their children’s illness. What should I do?

　　A:

　　National Health Commission has asked all localities to give full play to the role of medical associations, strengthen technical guidance to primary medical and health institutions, and improve the diagnosis and treatment ability of common infections and the efficiency of severe identification and referral.

　　Q:

　　Which hospitals are qualified to accept children with respiratory tract infection?

　　A:

　　National Health Commission has instructed all localities to publicize the information of medical institutions that can provide pediatric diagnosis and treatment services in the region, so as to facilitate the nearest medical treatment.

　　Q:

　　What should children do after they have a fever and cough?

　　A:

　　Large hospitals are crowded with people, waiting for a long time, and the risk of cross-infection is high. It is suggested that children with mild symptoms should first go to primary medical and health institutions and pediatrics of general hospitals. After seeing a doctor in a children’s specialist hospital, they can also be referred to primary medical institutions for follow-up treatment or home treatment through medical associations.

　　Q:

　　What conditions must the child go to the hospital for medical treatment?

　　A:

　　According to experts’ advice, children should take their children to see a doctor in time if they have ultra-high fever or persistent fever for more than three days, frequent cough affects their normal life, poor mental state or even drowsiness, increased respiratory rate or dyspnea, frequent vomiting, rash, headache or convulsions.

　　From: Xinhua Viewpoint

　　What do you think of when you mention sinkholes? Mysterious, dark, strange and exotic animals and plants. The discovery of the Hanzhong Tiankeng Group in Shaanxi, China in recent two years has attracted the attention of the world. Tiankeng Group has become another beautiful business card in Hanzhong after the Han culture of "Two Han and Three Kingdoms".

　　The discovery of the sinkholes in Hanzhong increased the number of sinkholes in China from 84 to 138, accounting for 39%, and increased the number of sinkholes discovered and confirmed in the world from 117 to 171, accounting for 31.6%, making it a well-deserved "first sinkhole group in the world". Jean Bottazzi, an internationally renowned cave explorer, praised the Shanjiayan Cave River Tiankeng in Ningqiang, Hanzhong as "the most beautiful Tiankeng in the world".

　　On March 13th, the academic seminar of Tiankeng Group in Hanzhong, Shaanxi Province, hosted by Shaanxi Geological Survey Institute, was held in Xi ‘an. Famous experts, scholars and government officials from home and abroad discuss practical issues such as the future development mode, protection and development strategy of Hanzhong Tiankeng Group, and plan the blueprint for the future road of Hanzhong Tiankeng Group.

　　The other side of the beauty of Hanzhong in Tiankeng Group

　　When it comes to Hanzhong, the mysterious, beautiful and unknown sinkholes will show another side of Hanzhong. Let the ancient Hanzhong be more aura and beautiful than the rigid and serious history.

　　What is a sinkhole? Luo Gan Zhou, director of Shaanxi Geological Survey Center, gave his own answer to this question in a relatively easy-to-understand language. Tiankeng refers to a geomorphological feature that the steep walls around it have a certain scale (generally more than 100 meters in depth and width) and develop in carbonate rock areas.

　　"It is inferred that the sinkholes in Hanzhong Tiankeng Group were formed 180,000 to 120,000 years ago, and the oldest can be traced back to 680,000 years ago. By studying the sinkholes, we can study the ancient geographical environment and climate, which can help us better understand the past. Unique terrain and special ecological environment under negative terrain are the best places for people to understand geological and climate changes. " Luo Ganzhou expressed the significance of tiankeng to the contemporary era.

　　Li Yichao, a senior engineer of Shaanxi Geological Survey Institute who has been engaged in tiankeng investigation for a long time, went deep into the bottom of tiankeng for exploration and research many times. Speaking of the exploration of the Tiankeng Group in Hanzhong, Li Yichao has endless stories. Interest and hardship coexist, and the tiankeng, which is rare on weekdays, is really charming but full of challenges.

　　"Most of the traffic in tiankeng is not very convenient. After getting off the bus, the team members have to carry more than 100 kilograms of equipment and food to walk for five or six hours. Generally speaking, we may walk for two minutes at most at a distance of more than 300 meters, but it will take more than an hour to go down the sinkhole. It takes more time to get up, it takes more than three hours to get up, and you can only get up and down with the help of lifting and rescue equipment. The degree of hardship can be imagined. Professional climbing gloves, our team members can wear out three pairs a month. It can be seen that this is difficult. The investigation is very hard, but our contribution is worth it. " Li Yichao said.

　　Luo Gan Zhou Xiang told Uncle Fang a little detail: "Once I went down the sinkhole, the road was very steep. I walked downhill for several hours, and my toenails were against my shoes. When I got back, I felt that my toenails were very painful and the color was a little black. A few days later, the toenail cover of my big toe fell off directly, which was particularly painful." Luo Ganzhou, who is over 50 years old, speaks lightly, but the dangers and pains may only be known to him.

　　Of course, the hardships are also full of fun. The light in the sinkhole is insufficient, and the darkness is beyond imagination. When two people sit face to face, they don’t move, and you may not feel anyone around you. But in the sinkhole, you can see transparent fish, meet all kinds of strange animals and plants, strange stalactites, and all kinds of strange geological structures and climate phenomena that are hard to see on weekdays.

　　Through many photos taken by investigators, it is not difficult to find that there are many spacious cave halls, mysterious and strange underground rivers, magnificent stalactites, stalagmites, edge stone dams and many other ingenious works from nature. For thousands of years, a unique primitive microclimate has been formed in the sinkhole, and the animal food chain and unique habitat in it are irreplaceable. In addition to these peculiar geological products, there are many animals and creatures, among which thousands of richness such as "Shafei Colored Grey Butterfly", "Blooming Pink Butterfly", "Elephant Cicada", "Green Scarab" and "Liliaceae Big Lily" were photographed by the respondents alone.

　　Flying cats are unique animals in Hanzhong Tiankeng. The flying cat’s scientific name is the flying squirrel, also known as "six unlike". It has a face like a fox, eyes like a cat, a rat with a pointed mouth, ears like a rabbit, paws like a duck, and a tail like a squirrel. Its wide fins between the front and rear legs can glide between cliffs and trees, with a maximum head and tail length of 1 meter and a weight of more than 7 kg. This kind of animal is very shy. It lies in the daytime and comes out at night. In addition, it is increasingly rare. It is not easy to see a living flying cat with one’s own eyes.

　　It is understood that the Hanzhong Tiankeng Group is the first tiankeng group with the highest latitude in the world discovered in the range of 32 ~ 33 north latitude. This discovery has important scientific value and fills the gap in the world karst geology research. There are 54 Tiankeng Groups in Hanzhong discovered this time, which are mainly distributed in Chanjiayan Town, ningqiang county, Hanzhong City, Xiaonanhai Town, Nanzheng County, Luojiaba Town, Xixiang County and Sanyuan Town, zhenba county. This discovery has increased the number of sinkholes in the world from 117 to 171, accounting for 1/3 of the global number of sinkholes, including 2 super sinkholes, 7 large sinkholes, 45 conventional sinkholes and 473 other geological relics.

　　Academician Yuan Daoxian of Chinese Academy of Sciences believes that the Hanzhong Tiankeng Group is located at latitude 32-mdash; — It was discovered for the first time in the range of 33 degrees, which made China moist in the tropics — The boundary of subtropical karst landform area has obviously moved northward, which has important scientific value. Reasonable protection, development and utilization of geological relics resources of Tiankeng Group will play an important role in promoting local economic development.

　　The important value of the discovery of the rare "Tiankeng Group" in Hanzhong lies in that it not only greatly enriches the tourism resources of geological relics in China and even the world, but also fills the blank of karst geology research in the world and increases the original samples of biological research. Through the study of its formation mechanism, conditions and evolution law, it will be of great scientific value to the study of paleogeographic environment and climate change in the north and south of China and even the whole world, and it will be praised by experts as a world-class "natural museum" that rewrites geological history.

　　Ambition to declare world geoparks and natural heritage

　　The geological park selected by UNESCO is a natural park with its geological scientific significance, exotic beauty and unique geological landscape, which integrates natural landscape and human landscape. The goal of UNESCO is to select more than 500 geological landscapes worthy of preservation and strengthen protection. At present, 35 geoparks in China have entered the UNESCO World Geopark Network List.

　　Whether it is a geopark or a world natural heritage, it is a leader in the global natural landscape, and its scientific significance and tourism appreciation significance are self-evident.

　　The reporter learned from different channels that at present, all parties are actively preparing for the world geopark and natural heritage declaration for the unique geological relic of Hanzhong Tiankeng Group.

　　The Hanzhong Municipal Government specially issued the Interim Measures for the Protection and Management of Geological Relics of Tiankeng Group in Hanzhong City, which made specific provisions on the scope of geological relics protection, regional management and protection measures, and legal responsibilities. Hanzhong will conscientiously do a good job in the protection of geological relics of Tiankeng Group in Hanzhong.

　　Hanzhong Municipal Bureau of Land and Resources said in a reply that Hanzhong will gradually promote the declaration of national and even world geoparks and natural heritage in due course.

　　It is understood that in October 2016, the Shaanxi Provincial Department of Land and Resources has awarded the provincial geological park construction qualification of Hanzhong Tiankeng Group; According to the provincial geological park planning to complete the construction task, Shaanxi Provincial Department of Land and Resources acceptance before the provincial geological park can be named. Provincial geoparks can only be declared as national geoparks after they are officially named for two years. Hanzhong will do a good job in basic work and declare national and even world-class geological parks and natural heritage according to relevant procedures.

　　Mao Xiaochang, a senior engineer of China Geological Survey, said in his speech that the formation mechanism of Hanzhong Tiankeng Group is different from that of South Tiankeng Group, and its biodiversity is also unique. Therefore, Hanzhong Tiankeng Group has the conditions to become a world-class in terms of rarity, scientificity, aesthetics and protection.

　　How to make good use of high-quality resources in developing and protecting economically underdeveloped areas

　　Tiankeng is a unique natural wonder, unique to karst conditions. In the natural landscape, it has a series of special tourism ornamental values and sensory attributes, such as rarity, strangeness, precipitousness, grandeur, beauty and unique ecological environment. At the same time, tiankeng always coexists with caves, underground rivers, strange peaks and rocks and other tourism resources, so it is undoubtedly a special super tourism resource.

　　It is understood that Chongqing Xiaozhai Tiankeng was opened to tourists in 1999, and Guangxi Leye Dashiwei Tiankeng Group is in the process of tourism development planning. In the future, the karst tiankeng scenic spot will add a bright spot to the world tourism industry.

　　How can Hanzhong miss such a good opportunity? In May, 2017, Hanzhong Municipal Bureau of Land and Resources and Hanzhong Municipal Bureau of Cultural Relics and Tourism jointly reported the topic to Hanzhong Municipal Government, suggesting that the world-class planning units should be selected, and in accordance with the principle of "development in protection and protection in development", Hanzhong Tiankeng Group’s geological relics protection and tourism development and utilization plan should be actively worked out, combining Tiankeng tourism with new formats such as culture, leisure, recreation, sports and research, and steadily promoting the geological relics protection and tourism development of Hanzhong Tiankeng Group.

　　Faced with such world-class tourism resources, it is reasonable for Hanzhong, which is economically underdeveloped, to have the impulse to develop and utilize it. However, tiankeng resources belong to non-renewable natural heritage resources, and once improperly developed, it will bring irreparable losses.

　　At the seminar, the reporter also heard different voices, but the voice of "protection first and moderate development" still dominated. For Hanzhong, where the economic strength is not strong and the pressure of getting rid of poverty is great, how to use the resources of Tiankeng Group to promote regional economic development and promote the local people to get rich and increase their income has become the main problem faced by the politicians.

　　The reporter had a detailed exchange with the deputy county (district) governors of zhenba county, Nanzheng District and ningqiang county. The conclusion is that everyone wants to use Tiankeng resources to promote the development of county economy, but this kind of utilization must be based on strict protection, and we should avoid rough development and homogeneous development of four counties, and start with high-end tourism and take a sustainable development path.

　　Zhou Qingfu, deputy county magistrate of zhenba county, told reporters that zhenba county will make rational use of Tiankeng, a high-quality resource, publicize Zhenba’s good ecological environment advantages on the basis of strict protection and reasonable planning, develop the Chinese herbal medicine industry around the high-quality ecological environment, and build Zhenba into a high-quality health care, pension, sports and experience base.

　　Wang Jun, the deputy head of Nanzheng District, also put forward his own views on the development of Hanzhong Tiankeng Group. Hanzhong Tiankeng Group should avoid large-scale development and give priority to protection. At present, it is difficult to develop Tiankeng with the ability of counties and districts, and it is easy to cause homogenization. Tiankeng is ecologically fragile and unrecoverable, and its safety is poor, so the development of Tiankeng should take the road of high-quality development.

　　Wang Longqing, chairman of Hanzhong CPPCC, believes that Tiankeng Group is the most precious, valuable and internationally influential resource discovered in Hanzhong so far. Establishing a research base for Tiankeng Group in Hanzhong is beneficial to the investigation, scientific management and development, geological monitoring and protection of Tiankeng Group in Hanzhong. Hanzhong City should take this opportunity, rely on the scientific research base as the platform, fully support the geological exploration work of the Provincial Geological Survey Institute, make overall consideration of the construction of the research base and geological museum, as well as security measures, attract world-class high-level talents to come to China for extensive exchanges, hire international professional teams to carry out development planning, and promote the scientific research and tourism development and utilization of Hanzhong Tiankeng resources in an orderly manner.

　　Mao Xiaochang, a senior engineer of China Geological Survey, also put forward his own views on the development of tiankeng. First, priority should be given to protection, and a high-end tiankeng adventure tour can be explored under the premise of protection. Tiankeng, a tourist resource, is not suitable for large-scale development. The location of the sinkhole should explore the mode of high-end in-depth tour, and professionals can be explored to explain professional geological and geographical knowledge to tourists, so that tourists can fully feel the unique charm of the sinkhole through five or six hours of in-depth tour. In addition, we can try to involve villagers in tourism, and develop some special projects such as geological and cultural villages and towns in the periphery to promote the development of local people.

　　Facing high-quality natural resources development and protection are not contradictory opposites. If we cling to the principle of protection and don’t make rational use of it, it will only be a good opportunity to delay development. If Jiuzhaigou clung to protection and didn’t seek development, it would be difficult to achieve such great achievements in local economic development today. However, development is not a kind of quick success and instant benefit, and it is a rational development path for the protection and local development of Tiankeng Group in Hanzhong to make long-term planning and rational utilization from the perspective of future generations’ long-term development. Presenting the most beautiful side of Hanzhong to the world may be the best protection for Hanzhong Tiankeng Group.